Driving breakthroughs in cancer research

Accurate next-generation sequencing methods for a comprehensive view of cancer-causing mutations

Cancer Sequencing Methods

Cancer sequencing using next-generation sequencing (NGS) methods provides more information in less time compared to traditional single-gene and array-based approaches. With NGS, researchers can perform whole-genome studies, targeted gene profiling, tumor-normal comparisons, and more. NGS also offers the sensitivity to detect rare somatic variants, tumor subclones, and circulating DNA fragments.

Oncology
Cancer Whole-Genome Sequencing

See a comprehensive view of the unique mutations present in tumor tissue.

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Cancer Exome Sequencing

Cost-effectively identify cancer-associated coding variants.

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Targeted Cancer Sequencing

Focus on sequencing a set of genes or genomic regions with known cancer associations.

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Cancer RNA Sequencing

Identify novel transcripts or determine which genes are overexpressed or underexpressed in tumors.

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Circulating Tumor DNA (ctDNA) Sequencing

NGS offers the sensitivity and specificity that researchers need to detect low levels of ctDNA.

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Featured Cancer Sequencing Research

 
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Exploring the Genetic Basis of Oral Cancer

Researchers use various cancer sequencing methods to uncover somatic variants, methylation changes, and other genomic alterations associated with a deadly oral cancer.

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Searching for Cancer Driver Genes
Searching for Cancer Driver Gene Expression Clues

Whole-genome sequencing of ctDNA samples enables researchers to analyze nucleosome patterns and infer the gene expression status of cancer driver genes.

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Role of Long Non-Coding RNA in Cancer
Deciphering the Role of Long Non-Coding RNA in Cancer

Researchers utilize RNA sequencing to reveal how lncRNAs could be used to identify, measure, and treat cancer.

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Illumina Cancer Methods Guide

New 2021 Methods Guide for Cancer Research

Updated with new research and solutions, this comprehensive guide provides an overview of NGS-based and microarray workflows for a broad range of cancer research applications. You’ll learn about various methods and their benefits, potential applications, and step-by-step guidance through each workflow.

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Clinically Speaking: An Oncologist and Pathologist Talk CGP
Clinically Speaking: An Oncologist and Pathologist Talk CGP

How in-house comprehensive genomic profiling at Weill Cornell benefits research and patients

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Using Analytics to Improve Cancer Diagnosis and Therapy Selection
Using Analytics to Improve Cancer Diagnosis and Therapy Selection

Developing and automating best-practice workflows that make analyzing, processing, and disseminating genomic data accessible to researchers and clinicians.

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Illumina Supports the Establishment of the Shanghai Genomics Alliance
Illumina Supports the Establishment of the Shanghai Genomics Alliance

More than 50 entities commit to strengthening the genetic testing industry through collaboration

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See More Cancer-Specific Content and Products

The user-friendly "Recommended Links" feature allows you to easily find content and products relevant to cancer research and/or a variety of other fields. You can access this option from the top of any illumina.com page.

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High-Throughput Genomics Technologies for Cancer Research

Learn how NGS-based cancer sequencing can provide a deeper understanding of tumor biology.

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Sequencing Limited or Low-Quality Tumor Samples

Find solutions that facilitate analysis of FFPE and limited (needle biopsy or aspirate) tumor DNA.

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Detection of Actionable Alterations in Tumors

Wagle et al. demonstrate detection of genomic alterations in tumor samples by high-throughput sequencing.

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Cancer Research Review

An overview of recent cancer research publications featuring Illumina technology.

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Cancer and Immune System Research Review

An overview of recent research publications exploring the interaction between tumor cells and the immune system.

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