AmpliSeq for Illumina TCR beta-SR Panel

FFPE-compatible panel for measuring T cell diversity and clonal expansion in tumor samples by sequencing T cell receptor beta chain rearrangements.Read More...
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Panel

AmpliSeq™ for Illumina® TCR beta-SR Panel

20031675


Library Prep

AmpliSeq™ Library PLUS (24 Reactions) for Illumina®

20019101

AmpliSeq™ Library PLUS (96 Reactions) for Illumina®

20019102

AmpliSeq™ Library PLUS (384 Reactions) for Illumina®

20019103


Index Adapters

AmpliSeq™ UD Indexes for Illumina® (24 Indexes, 24 Samples)

20019104

AmpliSeq™ CD Indexes Set A for Illumina®

20019105

AmpliSeq™ CD Indexes Set B for Illumina®

20019106

AmpliSeq™ CD Indexes Set C for Illumina®

20019107

AmpliSeq™ CD Indexes Set D for Illumina®

20019167

AmpliSeq™ CD Indexes Set A-D for Illumina® (384 Indexes, 384 Samples)

20031676

Accessory Products
Which accessories do I need?

Ampliseq™ cDNA Synthesis for Illumina®

20022654

AmpliSeq™ Library Equalizer for Illumina®

20019171

AmpliSeq™ for Illumina® Direct FFPE DNA

20023378

产品特色

AmpliSeq for Illumina TCR beta-SR (Short Read) Panel is a highly multiplexed targeted resequencing panel intended for use with multiple sample types, including formalin-fixed paraffin-embedded (FFPE) tumor samples. It is designed to measure T cell diversity and clonal expansion by sequencing T cell receptor (TCR) beta chain rearrangements. You can use a single pool of multiplex PCR primers, library reagents, and sample barcodes to generate libraries from DNA/RNA extracted from FFPE, whole blood, fresh-frozen tissue, or fluorescence activated cell sorting (FACS)-sorted cells.

Key features include:

  • High-Value Content
    Obtain comprehensive coverage of TCR beta chain sequences
  • Simple, Streamlined Workflow
    Prepare sequencing-ready libraries in a single day from FFPE, whole blood, fresh/frozen tissue, or fluorescence-activated cell sorting (FACS) cells
  • Low Input Requirement
    Generate high-quality sequencing libraries from as little as 10 ng of input RNA

The AmpliSeq for Illumina TCR beta-SR Panel is part of an integrated workflow that includes AmpliSeq for Illumina polymerase chain reaction (PCR)-based library preparation, Illumina sequencing by synthesis (SBS) chemistry and next-generation sequencing (NGS) technology, and automated analysis.

This ready-to-use panel saves you the time and effort of identifying targets, designing primers, and optimizing panels. It enables characterization of the hypervariable complementary determining region 3 (CDR3) of the TCR beta chain. This information can help immunology researchers understand immune function, autoimmune diseases, and immune-mediated adverse effects. 

Learn More About AmpliSeq for Illumina

Frequently Purchased Together

规格

计划推荐

仪器 推荐的样本数 读长
MiniSeq System Samples per run will depend on sample type. 2 × 151 bp
MiSeq System Samples per run will depend on sample type. 2 × 151 bp
NextSeq 550 System Samples per run will depend on sample type. 2 × 151 bp

产品比较

AmpliSeq for Illumina TCR beta-SR Panel AmpliSeq for Illumina Immune Repertoire Plus, TCR beta Panel
Method Amplicon Sequencing , 靶向DNA测序 , 靶向RNA测序 Amplicon Sequencing , 靶向RNA测序
Nucleic Acid Type DNA, RNA RNA
Specialized Sample Types Blood, FFPE Tissue Blood, FACS Cells, Fresh/Frozen Tissue
Species Category 人类 人类
System Compatibility MiniSeq , MiSeq , NextSeq 2000 , NextSeq 550 MiniSeq , MiSeq , NextSeq 1000 , NextSeq 2000 , NextSeq 550

Method-Specific Workflow Example

 

Supporting Data and Figures

 

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