Researchers are harnessing the power of high-throughput next-generation sequencing (NGS) and microarray technologies to conduct large-scale, global genetic analyses. This research often focuses on multifactorial genetic discovery of disease risk markers, and may involve looking for changes in genetic variants such as single nucleotide polymorphisms (SNPs), indels, splice variants, structural variants, and methylation markers.
High-throughput genomics studies with tens to hundreds of thousands of samples require fast, cost-effective tools. Illumina offers high-throughput sequencing and array technologies with unprecedented sample-to-analysis solutions and unparalleled collaborative expertise to meet these needs.
Illumina sequencing by synthesis (SBS) is a massively parallel sequencing technology that has revolutionized sequencing capabilities and launched the next generation in genomic sciences. The latest Illumina sequencers unite high-performance imaging with state-of-the-art flow cells to deliver massive increases in throughput.
With unmatched scalable throughput, tremendous flexibility for a broad range of applications, and streamlined operation, the NovaSeq 6000 System is the most powerful high-throughput Illumina sequencer to date, perfectly positioned to help scientists perform large-scale genomics studies. The system offers output of up to 6 Tb and 20 billion reads in < 2 days.View System
The Breast Cancer Atlas Project involves sequencing more than a million individual breast cancer cells to help researchers identify potential therapeutic targets.Read Interview
Implementing high-capacity NGS allowed the Deakin Genomics Centre to expand projects for species ancient and new, large and small.Read Interview
A large clinical study that integrates sequencing with imaging, multiomic technologies, and big data uncovers novel therapeutic targets for chronic diseases.Read Interview
Recent advances in sequencing technologies have allowed for the development of genomics-based strategies to assay GWAS SNPs for potential functional relevance. Powerful combinations of high-throughput experimental assays, single-cell approaches, and computational analyses are accelerating the ability to link variants to function, and, by extension, link genotype to phenotype.View Webinar
For labs preparing large quantities of NGS libraries, liquid-handling robots and other automation solutions provide a good option.Learn More
Sample multiplexing allows large numbers of NGS libraries to be pooled and sequenced simultaneously during a single run.Learn More
Single-lot shipments and other features empower clinical labs to reduce the frequency and cost of revalidating reagents and protocols.Learn More
Find information and resources to help simplify the process of setting up an informatics infrastructure and data analysis pipeline.Learn More
Learn how you can benefit from a laboratory information management system (LIMS) optimized for NGS, and find out what to look for.Learn More
Prenetics created a high-throughput genotyping laboratory to serve its growing customer base in Southeast Asia.Read Article
Researchers discuss large GWAS studies to identify disease-associated DNA risk loci and develop PRSs for clinical validation.Read Article
Resource planning and automated genotyping workflows allowed GPBio to achieve immediate efficiency and throughput gains.Read Article
A next-generation genotyping array for population-scale genetics, variant screening, pharmacogenomics studies, and precision medicine research.Learn More
A comprehensive microarray solution for production-scale genotyping of up to 50,000 single or multi-species custom variants.Learn More
This state-of-the-art LIMS facilitates high-throughput microarray processing and sample tracking, using advanced automation and precise robotic control.Learn More
National population genomics programs seek to integrate large, diverse data sets, combining clinical information with genomic data at scale in a learning health system.Learn More
Large-scale genotyping with arrays can identify variants associated with disease risk in large cohorts or populations.Learn More
Illumina sequencing technology uses fluorescently labeled reversible terminators to detect bases as they’re incorporated into growing DNA strands.Learn More