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Safe, secure, onsite

Reduce costs associated with developing, maintaining and scaling informatics infrastructure


BaseSpace Onsite Sequence Hub

Everyone can benefit from the power of BaseSpace Sequence Hub for the storage, analysis, and sharing of genomic data. For some labs, who have special storage, network bandwidth, security or compliance requirements, we created BaseSpace Onsite Sequence Hub – it’s safe, secure, and onsite.

BaseSpace Onsite Hub System

BaseSpace Onsite Sequence Hub is a local version of BaseSpace Hub that enables you to store, analyze, and share sequencing data from MiniSeq, MiSeq, MiSeq Dx (in RUO mode), NextSeq 500, NextSeq 550, HiSeq 2500, HiSeq 3000, and HiSeq 4000 systems. The storage and compute on BaseSpace Onsite Hub is matched to the needs of your instrument. The analysis capability includes the 25 most commonly used apps in BaseSpace Hub. Your data and results can be shared with any of your colleagues over your private network. Its intuitive web interface guides you through sequencing experiments, from sample management and run preparation through variant calling. Easy to install, maintain, and scale, BaseSpace Onsite brings simplified data storage and management, analytical informatics, and collaboration tools directly to you.

One Environmentfrom Sample to Answer

BaseSpace Onsite Hub was designed by research scientists for research scientists. You can start sequencing runs and track thousands of samples and experiments without complicated spreadsheets. It guides you through entering or importing sample information, placing or importing samples onto library prep plates, pooling libraries for sequencing, and setting up runs. Syntax errors and index compatibility are checked at each step of the process.

Seamless Integration with
with Illumina Sequencing Instruments*

The Illumina sequencing systems offer load-and-go operation. Simply load the flow cell(s) and reagents into the instrument, all of the run information is loaded from a sample sheet or imported directly from BaseSpace Onsite Hub (MiniSeq or NextSeq 500/550), and the sequencing run begins. Base calls and performance metrics are generated on the instrument, and can be instantly transferred to BaseSpace Onsite Hub for real-time, remote run monitoring, and saved to an independent local server, or both.

Push-Button Data
Processing and Analysis

Raw data are automatically converted to sequence reads and stored in BaseSpace Onsite Hub. Easy-to-use BaseSpace Apps simplify analysis of RNA-Seq, exome/enrichment, tumor normal, whole-genome sequencing (WGS), metagenomics, de novo assembly, amplicon, WGS long reads, WGS phasing, DNA methylation, visualization, FastQ Utilities, FastQ Quality Assessment for sequencing data.

Learn more about BaseSpace Apps

Data Sharing

Share run information and raw or processed sequencing data with colleagues instantly. BaseSpace Onsite Hub helps you to collaborate and exchange ideas easily.

*BaseSpace Onsite Sequence Hub supports: MiniSeq, MiSeq, MiSeq Dx (in RUO mode), NextSeq 500, NextSeq 550, HiSeq 2500, HiSeq 3000, and HiSeq 4000 systems. BaseSpace Onsite Hub does not support the HiSeq X Series systems.

A Secure, Safe, and Local Environment

BaseSpace Onsite Sequence Hub provides a safe and secure environment for NGS data. All data can be archived on any network-attached storage device. Only designated users can access the server. The data can be encrypted if necessary, and the system can operate on a local area network without a connection to the internet. Fault-tolerant storage and power supplies allow repairs to be performed in the lab, without requiring system downtime.

Affordable Installation, Maintenance, and Scaling

Illumina scientists install BaseSpace Onsite Sequence Hub within hours, and you can contact Illumina Technical Support with any questions ranging from library preparation to analysis. When more sequencers are added to the lab, server capacity can be scaled easily by connecting two or more BaseSpace Onsite Hub systems.

An End-to-End Solution, Designed for Research Scientists

With BaseSpace Onsite Sequence Hub, sequencing labs no longer require multiple third-party tools, or heavy reliance on IT and bioinformatics staff for common analyses. See how BaseSpace Onsite Hub provides a secure, end-to-end, easy-to-use, and affordable solution for next-generation sequencing informatics.

Access Data Sheet (PDF)

BaseSpace Onsite Hub Specifications

Review the server and storage specifications that ensure maximum safety.

View Specs

Which BaseSpace Hub is Right for Me?

BaseSpace Sequence Hub is available in both cloud (web-based) and onsite (fully localized) packages. Both the onsite and cloud versions of BaseSpace Hub require minimal configuration, installation, and maintenance. BaseSpace Hub is designed to run as an appliance or utility providing Software as a Service (SaaS) for genomic data storage, management, analysis, and sharing. Use the chart below to compare versions and determine which is right for you.

Have questions about BaseSpace Onsite Hub?

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Benefit Features
Easy to use for biologists
  • Push-button operation
  • Direct, automatic integration with Illumina instruments
  • Single platform for new Illumina bioinformatics tools
  • Direct integration with customer support
  • Wide variety of fully integrated BaseSpace Hub third-party Apps
  • Unlimited compute and storage scalability
  • Installed and running in hours
  • Scalable up to 6 nodes within a single, secure environment
  • Bench-top or server room configurable
Secure, reliable data transfer and storage
  • Data is automatically streamed in real-time during the sequencing run
  • Data encryption
  • Stored data is fully partitioned
  • The most efficient, reliable method for getting sequencing data to the cloud
  • 99.999999999% data durability
  • No additional backup data storage required
  • Data encrypted at rest and in transfer
  • All data is kept on-site
  • Can be run without any connection to the internet
  • Custom-designed, highly redundant server-class hardware
  • Maintenance and repairs on-site
  • Data encrypted at rest (configurable)
  • Can work with existing data archival solutions
Collaboration through secure sharing
  • Data is stored in the system as a centralized point of access
  • Extensive user-controlled data access and permissions allows data sharing and transfer between accounts
  • Raw or processed data can be instantly shared with anyone, anywhere in the world
  • Data is easily accessed for review and comparison by others in the field
  • Data is available to local users
Evolving informatics application catalog
  • Both Illumina-created and third-party apps are available in BaseSpace Hub
  • Apps can be combined into any number of analytical workflows
  • Anyone can use an app in BaseSpace Hub through an easy-to-use clickable interface
  • Anyone can quickly and easily create a customized app in BaseSpace Hub using any programming language
  • Illumina-created BaseSpace Core Apps are available for fast and easy data processing
BaseSpace Sequence Hub is intended for research applications and not for diagnostic or clinical use. It is intended to be used with Illumina research products only.

Additional Resources

BaseSpace Onsite Hub Support Find user guides and additional technical information. See BaseSpace Onsite Hub Support

BaseSpace Onsite Hub View Video BaseSpace Onsite Sequence Hub allows users to access their next-generation sequencing data anywhere.